I've got one of my museums to level 40 and have around 400 guests + 61 staff in my museum. The frame rate has dropped massively when running on fast speed and is making the game almost un-playable. I have tried turning the Status Icon Filter to vital icons which made a difference when my museum was slightly smaller but as it's grown it's gotten laggier again. All the animations have slowed too like the game lags when letters come in and I get notifications pop up, I've also noticed that donation bins take longer to empty animation wise. Animations are all starting to not run as smoothly and it's making it quite hard to play.